Build a multidisciplinary research network involving experts of technical and medical
disciplines to merge their expertise and exploit possible synergies for the development of reliable and sustainable in
vitro cell models of healthy and aged bone tissue treated with or without QMR (Quantum Molecular Resonance).
Train a cohort of scientists and technologists in exploiting the model features to increase knowledge on the effects of aging on bone biology and mechanobiology, and on bone response to QMR, to leverage the use of cell models in clinics and basic/industrial research labs.
Bone aging reduces the quality of life of the elderly and puts social and economic burden on society. Aging bones fail more easily when challenged mechanically or with toxicants or pollutants,
and respond differently to drugs than healthy bone.
To personalize therapies and enable better preventive care for the elderly it is essential to develop reliable and sustainable in vitro models of aged bone tissue alternative to animal tests which often fail to capture human-specific features.
Networking
The networking activities planned in
REGENERATION will generate new knowledge about the mechanisms of bone growth, regeneration and aging, about drug and technologies development for bone pathologies and will study the effect of QMR stimuli in cell proliferation, differentiation and trasfection by in vitro and computational models.
7 Participants
4 Countries
